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Doxycycline: Phenobarbital has been proven to shorten the 50 %-life of doxycycline for so long as 2 months immediately after barbiturate therapy is discontinued.If taken at superior doses, Nembutal can suppress important organs and bodily features, such as speech and mobility.Anticoagulants: Phenobarbital lowers the plasma levels of dicumarol (iden